The project leading to this application has received funding from the European Union’s Horizon
2020 research and innovation programme under grant agreement No 667387

Trainings organised in PPIMC

Training performed by Dr Cristina Iojoiu, Directeur de Recherche, CNRS, LEPMI (Laborator d'electrochimie si fisico chimie des materiales si interfate) -Grenoble-INP, Francea, 16-17.11.2017 

Dr. Cristina Iojoiu made a training on Electrolytes polymères pour les piles à combustible, accumulateurs lithium, cellules solaires à colorant. Due to renovation works in the institute, the training was made in the library of Petru Poni Institute of Macromolecular Chemistry.
After the training Dr Iojoiu discussed with the SupraChem Lab team members. On 17.11.2017 Dr Iojoiu also made a serious analyse of the SupraChem Lab project due to the fact that starting with May 2017, Dr. Iojoiu was included in the International Advisory Board (IAB) of the SupraChem Lab project. With the occasion of this training Dr Iojoiu had the opportunity to meet the research team and also to understand the SupraChem Lab project objectives and activities.
Dr. Iojoiu provided the SupraChem Lab management team important suggestion in order to speed up the group activity. Dr. Iojoiu was also happy to exchange information and opinion with Prof. Abadie who was also her supervisor for her PhD thesis.

Fourth SupraChem Lab training event 17.09.2017 - 19.09.2017

The second training event organised during the second reporting period (training no 4 of the project) was organised between 17.09.2017 - 19.09.2017 in the library of ICMPP. The initial idea, as suggested during the review meeting by Dr Argiris LASKARAKIS, was actually to organise practically a workshop were the members of the SupraChem lab to meet with several research personalities and to share research results. Unfortunately we could not organise at this level for 2017 due to the resignations of Dr. Barboiu and the fact that Prof Abadie the new SupraChem Lab ERA CHAIR has started his new position with 01.09.2017. Also the conference hall of ICMPP was blocked  due to an important renovation  project that is implementing in ICMPP.
However the training involved more trainers than usually and each subgroup of SupraChem Lab team has presented its activity.
The September 2017 trainers were:

  • Prof. Aggr. Dr Francesca Mocci, Dipartimento di scienze Chimiche e Geologiche, Universita' di Cagliari, Italy: The scientific activity of Dr. Mocci is mainly directed to the study of conformational preferences of organic and bio-organic molecules and of their interactions with other molecules and ions; these researches are carried out by means of modeling techniques often combined with NMR techniques. The employed computational techniques are based either on quantum or classical mechanics, and recently she became involved in the development of coarse grained models. Part of these studies involve collaborations either with national or international groups.
  • Prof. Dr Danny O'Hare CChem FRSC, Reader in Sensor Research, Department of Bioengineering, Imperial College, London, UK: Dr. O’Hare is a Chartered Chemist and member of the Royal Society of Chemistry, the Electrochemical Society and British Society for Matrix Biology. After completing post doctoral work in the PFSG on electrokinetic characterization of articular cartilage, he held first the post of Lecturer, then Senior Lecturer in Analytical Chemistry at School of Pharmacy & Biomolecular Sciences, University of Brighton 1992-2001. He is a Member of the Advisory Board for Analytical Abstracts (Royal Society of Chemistry).
  • Prof. Dr Aatto Laaksonen Department of Materials and Environmental Chemistry, Division of Physical Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden: Research interests in general: Bio & Materials modeling/simulation across long time/length scales; Method development: first-principles, atomistic simulations and coarse-grained modeling. Research interests in DNA: structure, dynamics, hydration, manipulation, damage and repair.Computer simulations of DNA (MD & MC) since 1983.
  • Dr. Porzio William, C.N.R. – Istituto Per Lo Studio Delle Macromolecole (ISMAC), Responsible for the Morphology and Structure Laboratory, Milano, Italy: Scientific Activity: Structural, thermal and morphological characterizations of polymeric material, degree of crystallinity and orientation, crystallite dimension and perfections, Physico-chemical properties of polymers, Structural determination of monomer, oligomer and polymer macromolecules as crystals, powders, fibers and films of controlled thickness from monolayer to microns, Use of variable temperature XRD apparatus to investigate structural evolution, i.e. phase transition, polymorphism, melting or freezing, Preparation of thin films by casting, spin- or deep-coating, high-vacuum evaporation (OMBD technique), film patterning for optoelectronic device preparation.

The meeting Agenda

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Third Suprachem Lab indoor training 31.05.2017 - 01.06.2017

The training was performed by two experienced researchers from Fraunhofer-Institut für Biomedizinische Technik (IBMT), Germany:

  • Dr Nadine Wilhelm Group Manager for Preclinical Nanomedicine group: The working group of Preclinical Nanomedicine is focused on the development and evaluation of new therapeutic approaches based on nanoparticles. Nanoparticles are a flexible transport platform for various applications such as tumour targeting, gene therapy or neurodegenerative diseases. Biocompatible and biodegradable proteins and polymers such as human serum albumin (HSA) or the polymer polylactic acid (PLA) form the backbone of the developed nanoparticles. For the directed targeting, the nanoparticles are modified with cell-specific ligands. The specific nanoparticles transport drugs directly to the target cells without impairing or harming neighbouring cells. Thus, side effects of e. g. toxic drugs such as cytostatic agents for the tumour targeting can be reduced. For the genetic modification of cells, the biocompatible nanoparticles are loaded with DNA, RNA or small molecules. The aim is to develop efficient gene delivery systems for primary and stem cells to replace viral-based delivery systems in gene and cell therapy.
  • Dr. Sylvia Wagner, Head of Department Bioprocessing & Bioanalytics: The activities of the Bioprocessing & Bioanalytics Department can be summarized under the heading of "nano and human". One aim is to address the question as to which influences nanomaterials have on humans and the environment. Answers can be found within the field of nanotoxicology. Here, the two working groups Nanotoxicology and Biomonitoring & Biobanks are leading the government-funded (BMBF ) project “NanoUmwelt” in which the risks to the environment of synthetic nanomaterials, many of which have been around for quite some time, in cosmetics and food, for example, are analyzed. To evaluate such questions with regard to the risk potential of contaminants for humans and the environment in the future, and to make it possible to give recommendations for official regulatory procedures, samples of human and environment are being collected, characterized and cryopreserved by the working group Biomonitoring & Biobanks by order of the Federal Environment Agency inter alia. As there are not many suitable detection methods for most of the nanomaterials, both working groups are researching applicable analysis methods.

The Training Agenda

On the last day of the training (02.06.2017) a team building event was organised, giving the opportunity to the members of the SupraChem Lab group to have open discussion with the two researchers from Germany

Training performed by Prof. Marc J.M. Abadie, University of Montpellier, France, 28.02 – 01.03.2017

Prof. Marc JM Abadie was invited to give advance training on UV/EB Curing-Principle, 3D Structures, Coatings and Thin Film Technologies between 28.02 – 01.03.2017. The training was divided in 8 sections organised during two days 9.30 -12.30 the Conference Room of ICMPP and with extend participation. In the afternoon individual discussions with the members of the SupraChem  Lab group were organised in IntelCentre meeting room.
The visit of Professor Abadie in February 2017 was extremely important for the development of the SupraChem Lab as it coincide with the resignations of Dr. Barboiu. During the visit Prof Abadie had the chance to meet and discuss both with the SupraChem Lab team and with the management team and he started to be interested in working and supporting the new group. 


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Training performed by Dr. Alice Cristina Mija Associate Professor HDR at University of Nice Sophia Antipolis, France, 07-10.11.2016

The training was organised by the SupraChem Lab management team in IntelCentre at P. Poni Institute of Macromolecular Chemistry between 07-10.11.2016 on the topics:
- 07-08.11.2017: Auto-organized supramolecular systems by anisotropic self-assembly
- 09.11.2017: Biobased polymers and matrix to develop green composites
- 10.11.2017: Design of sustainable thermosets: from synthesis to properties control
The courses have been performed in the conference room of ICMPP and colleagues from the Institute were also invited between. The training program was 9.30 – 12.30 with QA sessions and coffee brake at 11.00. Beside the training sessions, individual/direct discussions with the SupraChem Lab Team was organised in the meeting room of IntelCentre. A special discussion session was reserved on 10.11.2017 with the management team of the SupraChem Lab project (Dr. Mariana Pinteala and dr Teodora Rusu) in order to establish a cooperation strategy between Dr. Mija and the SupraChem Lab Team in terms of joint project proposals (including H2020 participation) and mobility.

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Training performed by Professor Cristina Has - UNIVERSITÄTSKLINIKUM FREIBURG, Klinik für Dermatologie Molekulare Dermatologie, Germany, 31.10.2016

Prof Cristina Has was invited in the framework of Romanian Mobility Grant and on 31.X.2016 the SupraChem Lab Management Team have organised a joint action together with collaborators from the "Al. I. Cuza" University, Iaşi, Romania , “Gr T Popa” University of Medicine and Pharmacy and ”St. Mary” Pediatric Emergency Hospital Iasi Romania,  in the conference room of P. Poni, Institute of Macromolecular Chemistry.
The program of the meeting was:

  • 9:00-10:00 Ichthyosis lecture - Cristina Has (UNIVERSITÄTSKLINIKUM FREIBURG, Klinik für Dermatologie Molekulare Dermatologie)
  • 10:00-10:30 Genetics elements in ichthyosis - Cristina Rusu, Lacramioara Butnariu, Elena Braha, Monica Panzaru, Lavinia Caba, Roxana Popescu, Setalia Popa, Eusebiu Vlad Gorduza(”St. Mary” Pediatric Emergency Hospital, “Gr T Popa” University of Medicine and Pharmacy)
  • 10:30-10:40 Clinical mimics of Ichthyosis - Anca Chiriac, Liliana Foia*, Vlad Eusebiu Gorduza *(Nicolina Medical Center, *“Gr T Popa” University of Medicine and Pharmacy)
  • 10:40-10:50 Dyskeratosis congenital- Ingrith Miron, Otilia Frasinariu, Laura Trandafir (”St. Mary” Pediatric Emergency Hospital “Gr T Popa” University of Medicine and Pharmacy)
  • 10:50-11:10 Ichthyosiform erythroderma - Daciana Branisteanu, Gabriela Stoleriu, Andreea Dimitriu, Daniel Branisteanu (“Gr T Popa” University of Medicine and Pharmacy)
  • 11:15-12:00 Coffee break
  • 12:00-12:20 Collodion baby - Alina Murgu, Bogdan Stana (”St. Mary” Pediatric Emergency Hospital)
  • 12:20-12:40 Congenital Ichthyosis - Petronela Colbu, LauraTrandafir (”St. Mary” Pediatric Emergency Hospital)
  • 12:40-13:00 SEM and ATR-FTIR techniques for studying Hair Shaft Anomalies in Netherton syndrome - Florica Doroftei, Adina Coroaba, Caius Solovan(“ P. Poni” Institute of Macromolecular Chemistry, Romanian Academy)
  • 13:00-13:30 Local treatment of Ichthyosis: therapeutic formulations - Lenuța Profire (“Gr T Popa” University of Medicine and Pharmacy Iasi, Romania)
  • 13:30-13:50 Psychosocial implications of Ichthyosis. The role of psychologist and psychological counseling - Soponaru Camelia (Department of Psychology, "Al. I. Cuza" University, Iaşi, Romania)
  • 14:00-17:00 Discussions with the SupraChem Lab Team

The Second SupraChem Lab indoor training 25-27.09.2016

The second SupraChem Lab indoor training was organised together with the first SuparChem Lab Management Meeting. The training was performed by three experienced researchers from prestigious EU Institutions and by the SupraChem Lab ERA CHAIR:

  • Prof. João Goulão Crespo - Professor of Chemical Engineering at the Faculty of Sciences and Technology - Universidade Nova de Lisboa, Portugal, where he is Vice-Rector for Research and Innovation. Former Vice-President of Fundação para a Ciência e a Tecnologia (Portuguese National Science Foundation) and former President of the Scientific Council of the Faculty of Sciences and Technology at NOVA. Member of the editorial board of Journal of Membrane Science, Journal of Biotechnology, and Desalination and Water treatment. Member of “Academia de Engenharia”, Portugal, external member of the EPSRC, United Kingdom, President of the Scientific Committee of the “Institut Européen des Membranes, Montpellier, member of the Steering Committee of the “Pôle de Chimie Balard”, France, and external expert of the “Commission des Titres d'Ingénieur”, France.
  • Prof. Stéphane Vincent - Professor at the Faculty of Sciences, Director of the Bio-Organic Chemistry Laboratory, Namur University, Namur, Belgium: Master and PhD degrees in bioorganic chemistry from the Université Louis Pasteur (Strasbourg, France) with Charles Mioskowski. After postdoctoral studies, first at The Scripps Research Institute in the research group of Prof. Chi-Huey Wong and then in Strasbourg with Prof. Jean-Marie Lehn, he took up a permanent position as a CNRS researcher in 2001 at the Ecole Normale Supérieure (Paris). In 2004, he began an appointment at Université de Namur (Belgium), as Assistant Professor then Full Professor in 2014. His research interests include the glycosciences, biocatalysis, and mechanistic enzymology.
  • Dr. Marc Baaden, Laboratoire de Biochimie Théorique, CNRS, Paris, France; Expertise in : invent simulation algorithms to reproduce and predict physical properties of biomolecules either in vitro or in the cell, and understand the molecular or conformational factors responsible for the biological functions of living systems, and diseases.
  • Dr. Mihail Dumitru Barboiu, SupraChem Lab ERA CHAIR and senior researcher PPIMC and the Institut Européen des Membranes in Montpellier, France received his PhD in 1998 from University of Montpellier II before spending 2 years as Associate Professor at College de France, with Prof. Jean-Marie LEHN at the Supramolecular Chemistry Laboratory, at University Louis Pasteur, Strasbourg. Since 2001, he has been CNRS Research Fellow and then Group Leader/Senior Researcher at the Institut Européen des Membranes in Montpellier, France and Associate Professor at University Politehnica of Bucharest, Romania. A major focus of his research is Dynamic Constitutional Chemistry of functional adaptive systems: biomimetic membranes, biosensors, etc. Authors of more than 130 scientific publications, Dr. Barboiu has received in 2004 EURYI Award in Chemistry.

September Training Agenda

First SupraChem Lab indoor training 05-06.05.2016

The training was performed by several experienced researchers from prestigious EU Institutions:

  • Prof. Bernold Hasenknopf, Professeur, Université Pierre et Marie Curie, Institut Parisien de Chimie Moléculaire, Paris, France UMR 7201. Group leader of the Supramolecular Chemistry group (since 01/2014 part of Glycochimie organique et biologique et chimie supramoléculaire). Supramolecular chemistry, Polyrotaxanes for bimodal imaging, Molecular mechanical switches, Functionalization of polyoxometalates, Applications of polyoxometalates in biology (10/96, Ph. D., Université Louis Pasteur, Strasbourg: Self-assembly of supramolecular, inorganic architectures - Circular helicates and heterohelicates; Supervisor: Prof. Jean-Marie Lehn).
  • Prof. Olof Ramström, Royal Institute of Technology, Department of Chemistry / Organic Chemistry, Stockholm, Sweden;Expertise in: Dynamic combinatorial chemistry, in which chemical libraries are synthesized and forced to adapt to an external selection pressure; Biomimetic, supramolecular chemistry - biological systems such as receptors, enzymes and antibodies are being mimicked to create new biomimetic materials and structures. Advanced Materials- surface-confined polymerisation protocols and photochemical control of surface properties. Molecular Recognition and Biological Interactions - design and synthesis of new ligands/inhibitors and the study of their interaction with receptors and enzymes are central to all aspects of our research.
  • Dr. Marc Baaden, Laboratoire de Biochimie Théorique, CNRS, Paris, France;Expertise in : invent simulation algorithms to reproduce and predict physical properties of biomolecules either in vitro or in the cell, and understand the molecular or conformational factors responsible for the biological functions of living systems, and diseases.
  • Prof. Lenuta Profire, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania;Expertise in: new aminocage compounds as NMDA receptor antagonists for neurodegenerative diseases; Research on methylxanthine compounds field; Pharmaceutical substances with action on sympathetic nervous system (adrenergic drugs)
  • Prof. Liliana Verestiuc, Vice-dean Faculty of Medical Bioengineering, Department of Biomedical Sciences, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania; Expertise in: Research in the field of synthesis of new biomaterials by capitalizing upper-products of the leather industry; advanced processing of materials chemically ie. modified collagen and others biopolymers and their synthetic polymers for obtaining new medical products

The meeting Agenda